Can Alpha Lipoic Acid help restore your sense of smell?
Anosmia. No sense of smell. Mine used to be normal, though seasonally attenuated by an allergy to pollen. I seem to have been without it forever now, though I suppose it must simply have grown more intermittent over the years until I realised I couldn’t remember what anything smelled like any more.
Doctors? Well, yes, you should always go see the doctor, see what pills he can prescribe for you, but my own doctor isn’t the most hopeful nor encouraging of healers – his most endearing mannerism is his slightly leaden patience, his least endearing a sorry shrug of the shoulders and the phrase: “There is nothing we can do.” Over the years he has conditioned me into believing the same of all ailments, that the best I can hope for is that the body will heal itself in those cases where it can, and that we have to simply adjust to living with those cases where it can’t.
The surgeons at the ENT department were a little more hopeful, offering me a handful of steroids and saying that if they didn’t work they could remove the nasal polyps their cameras had also revealed. (Polyps are harmless little outgrowths from the mucus membrane). The steroids worked, restoring a supernormal sense of smell in a matter of days, but this only lasted a few months, then it was back to anosmia as usual. As for the surgery, I know people who’ve had their polyps removed. They say it hurts, you’re on sickpay while it heals, it doesn’t work, and the polyps grow back in a few years anyway. The ENT surgeons gave the same pessimistic prognosis, so it didn’t take me long to decide on that one. If your polyps are so big you can’t breathe through your nose, then it’s worth doing, but otherwise,… probably not.
I think nasal polyps are a red herring anyway. True they often accompany anosmia, and are sometimes cited by medical professionals as being the cause of it, but I think they’re more likely a symptom. I still have polyps, but my sense of smell can be restored by steroids, which work by reducing inflammation. Ergo, I believe the cause of anosmia is inflammation, probably of the mucous membrane, which also contains the nerves that help us smell. Perhaps as the membrane swells, it stretches the nerves or even damages them, I don’t know, I’m speculating now. That would be my avenue of research if I were a medical man, but I’m not. I just want my sense of smell back.
Of course, you can’t live on steroids. Taken in the longer term they’re nasty things. Indeed I’m of the view it’s a bad idea to be on any kind of pharmaceutical for life, unless you’d be dead without it. What you need is something more natural and for which there are no known side effects, that the aim should be to kickstart the body’s own healing mechanism, not to find a permanent crutch for its apparent failings.
Fortunately, there are no end of “natural” methods for curing anosmia. Unfortunately I must have tried all of them, but to no avail. Then, about six months ago I came upon information about Alpha Lipoic Acid (ALA), a common, inexpensive food supplement that’s used as a natural anti-inflammatory. Medical reports, whilst not conclusive, were encouraging, that boosting your intake of ALA could help in recovering the sense of smell.
I’ve been taking it now, as the title of this piece suggests, for 200 days, and have experienced some welcome improvement. I can no longer say I have no sense of smell whatsoever. It’s intermittent, present for some parts of the day absent for the rest. I’ll go for a few weeks without anything, and then a few weeks intermittently smelling things again. The improvement is small, halting, tentative, but seems to be gathering strength. As of now, even at it’s best, I have to say the sense is still severely impaired, responsive only to the strongest of odours, also curiously selective. By contrast Steroids will reveal to me the richly varied texture of background odours as I move from place to place. Such things are still beyond my grasp, but there is movement in the right direction. I’m taking nothing else, so it has to be the Alpha Lipoic Acid.
Results were not immediate. I began taking it at the start of 2015, and noticed no improvement for the first 100 days. Then I began to get my first inklings.
The medical studies involved a dose of 600 mg per day. The recommended daily maximum (as a food supplement) is 200mg. I didn’t want to exceed the recommended dose that much, so compromised on 400 mg. (200 in the morning, 200 in the evening). I take it in capsule form, with food. If you take it on an empty stomach it’ll give you indigestion.
So anyway, yes, it’s taken a long time, and even after 200 days it’s still mostly a blank with just the occasional heady rush of scent, but welcome all the same. I’ll report back in another 100 days, and let you know if there’s been any further improvement.
One other thing I should mention here, as I’ve mentioned elsewhere in this blog, is the effect of alcohol. This may not effect everyone, but in my case at least, drinking it will set back recovery by days or even weeks. I can get away with it provided I don’t exceed the medically approved limit of 1 unit ABV per hour, and a maximum of 4 units per day. Any more than that and the body struggles to metabolise it. I can only speculate it’s causing an inflammation of the mucous membrane. If you’re struggling with anosmia then, it’s worth going tee total for a couple of months to see what happens. It’s not easy I know- most of us who like a drink are more hooked on alcohol than we suspect – that is until we try quitting, and then we realise it only too well. I’m down to a bottle of wine a week now – but not all at the same time.
The only other thing I found that helped with Anosmia was acupuncture. It took about 5 sessions but my sense came back quite strongly – again acupuncture is an effective anti-inflammatory. In my case it didn’t last very long though, but I was also drinking more than the medically approved guidelines at the time. I hadn’t made the link back then, but I’ve no doubts about it now.
If I was starting out again, looking for a cure, I’d say, for the quick hit, quit drinking and get some acupuncture. You should see positive results after five to ten sessions. Any more than that and it isn’t going to work. But start drinking again, and you’ll lose the benefits. For the longer road, quit drinking and start taking Alpha Lipoic Acid. You should see the first (modest) results within three to six months, but keep drinking – even modestly – and the results will be choppy to non existent.
Hello Michael, curious to know why you would need to stop drinking if you want positive results with acupuncture and alpha lipoic acid. Is one able to enjoy a glass of wine with dinner? One bottle of wine a week as you mention is not a lot, so surprised it would be an issue.
I too am trying the ala and acupuncture. I have been taking ala for about a month. Started with 100 mg for first two weeks, now taking 400 mgs a day for last two weeks, as well as 400 mg of l carnosine a day, along with a multi vitamin and pro-biotic. I feel there has been slight improvement. I guess I need to be patient. Acupuncture has shown me some small improvement also, but doesn’t seem to last. Have been 4 times.
I have had this situation for 4 months. Not sure how it started, but believe it was a blend of a bad cold, antibiotics, and a cold medicine spray (oral, not nasal). Really not sure which is so frustrating.
I am optimistic though that time will heal us both and all those suffering from this.
Thanks,
Suzanne
Hi Suzanne, thanks for dropping by.
This piece is fairly reflective of how I felt after 200 days. I’m still careful with alcohol, but a glass with dinner is a nice thing to have, and probably okay. It’s something I noticed more if I shared a bottle of wine of an evening – this is about 5 units – the sense of smell would definitely drift off and be missing all the next day. Since my sense of smell was feeble and intermittent anyway at this stage, I concluded the alcohol was interfering with my recovery, so I came down on it pretty hard.
I’m a bit more relaxed about it now my sense of smell is much better, but for me at least it pays to be careful. If you don’t notice any difference after drinking, you’re probably not sensitive to it in the same way as me and don’t need to worry about it, so enjoy that glass with your dinner.
Interesting to hear of your results with acupuncture. It took about five sessions for me to notice a difference, but like you the effect didn’t last.
Good luck with the ALA. I think it’s really helped me a lot. My sense of smell is mostly normal now, though I went without it for years. It does take a while though to see solid results.
Best wishes
Michael
Hey Michael,
Just wondering what happened since your last post, did you continue to take the ALA supplement and still do so? How is your sense of smell? My fiance lost her sense of smell at the end of 2014, and she still doesn’t have it back. I’m wondering if she starts taking ALA, if it will come back..
Thanks!
Sam
Hi there, yes I still take it. My sense of smell is fairly normal now. Just the occasional period of a few days when it will drift off again. Some days it’s very strong. I’m the sure ALA was a factor.
All the best,
Michael.
Awesome, thanks for that feedback! I’ll let her know to get on the ALA train for a good period of time and hopefully that helps.
Thanks!
Sam
Hello…I lost my sense of smell and taste after my first ever sinus infection at 48 yes old. I was told I had no polyps or tumors so that’s good. My ENT Suggested I take ALA 600 MG twice a day. I’m on day 30…but nothing yet. It’s depressing but I’m trying to stay positive.
Hi Linda, I took 500 mg a day and it was a while before I noticed any difference. (200 days) . Do stay positive, and best wishes for your recovery.
Hi Michael,
I was somewhat relieved to read that I am not the only person who has been experiencing such similar issues with the lack of sense of smell.
My problems started approximately 8 years ago and like others have mentioned, I belive it all started with rhe really heavy cold and as I was recovering it was evident that my smell was not!! It was strange at first and for some time I didn’t pay too much attention but then when it wasn’t coming back, it really dis start to worry me.
Similar to your story, I too was prescribed the steroids and all the nasal sprays of this world but to be honest I felt they only made it worse.
Then the camera was showing the polyps, which I got removed. My smell came back but to only disappear again in a few months. Unfortunately I too got the shrugged shoulders of “there’s nothing else we can do”.
I wish to mention that my sense seems to come back when I partake in heavy sports activities, such as sprinting or forms of HIIT training. Although this is always temporary and seems to disappear within that same day.
You mentioned alcohol’s role and that is so interesting because I too have noticed this to be the case, particularly with wine!
In fact I seem to experience not only loss of smell (after short comebacks) but also have a bungged up feeling.
Recently I had tensolitis and was prescribed some antibiotics for it. Since day 1 of taking them I have noticed the smell coming back. In fact it is the best I ever remember! I can only presume this has something to do with it?!
I only have one more day of these to take and therefore have not been taking any alcohol but my wife opened a nice bottle of red and she had me trying it (and I mean literally trying it) within a short period my sense started to disappear!!
Perhaps the other reason that my smell is back is because I havent taken any alcoholic drinks for the last 3 weeks! But then again there has been times during the last 8 years where I was off drink totally for months and that didn’t make any significant difference.
Apologies for ranting on with my story but it feels somewhat liberating to share with others who understand what it feels like to have one of your senses gone!
Can you please provide an undate as to how your smell is today? Are you still seeing improvements with the use of ALA?
Also any particular brand or where would you purchase yours from?
Look forward to hearing from you.
Regards
Fisnik
Hi Fisnik, thanks for writing. It’s always interesting to hear of the experience of others with anosmia. I’d say my sense of smell is fairly stable now, roughly normal – sometimes very sharp, sometimes less so, which I think is normal anyway. The alcohol is still an issue and can kill it for days, but I’m aware of the link now so try not to overindulge (too often anyway). I get my ALA from my local health food shop (Chorley Health Foods). It’s their own brand. I take 250mg per day, most days. It took about a year before I saw a significant difference, but it’s great now to have a sense of smell I can rely on – such a big difference from a few years ago when I thought I’d never get it back.
Best wishes for your ongoing recovery.
Regards
Michael
It’s been 17 yrs since noticing my sense of taste/smell (t/s) being compromised. At the time I was a Certified Pool Operator. One of my daily duties was to feed pool chlorinator. After shutting pump down, I opened the chlorine gas valve releasing chlorine gas in the air. On occasion this very strong odor sent me running out of the pump room, gasping for clean air! My sinuses also felt severely tingly. Over the yrs I noted my sense of t/s deteriorating. Perhaps 5 yrs later (~2005) it was 95% gone. Since then I noted that I could t/s for about 20 seconds at beginning of meals. The t/s level was only about 10%. This has caused some depression. I also was under the care of an ENT who Rx steroids, nasal spray. I followed this regimen for ~6 mo with no improvement. IMO, it worsened. I came across ALA info today and thought I’d give it a shot. One post positively stated that taking ALA in morning allowing at least 6 hrs before imbibing in alcohol. I’ll prob go on wagon at the onset for awhile before reintroducing alcohol at low level. Thx to all above for sharing!
I am a painter of 20 years & when I was a teen I chain smoked pot & cigarettes for a couple of years – Very poor sense of smell ever since even though I smoked neither in all that time. I am doing EDTA via suppository for detox & added ALA. It stings like hell in suppository so I only did it for two days now I use oral. Plugging 600mg for 2 days restored my sense of smell 3x as good and I was not expecting it at all. I went for a walk down town & realized – Hey I can smell again. Basically if its intermittent its prob because of oral absorption. If you can get it in your blood stream it has a dramatic affect in 2-3 days
Hello Michael, I realized that my sense of smell and taste were really gone about three years ago. It had been diminishing for many years without my really deciding something was wrong. I have never smoked, have generally good health, and have thought that an overuse of antihistamines for allergy might have contributed to anosmia.
Have you seen the correlation with thyroid dysfunction (underperforming thyroid, hypothyroidism)? I have read a lot about that being a possibility. Because of your writings on ALA I did start to take it at 600 mg/day for about three months. But I am curious as to why you thought, or what you read about ALA, that lead you to believe ALA might be a useful treatment for anosmia.
I somehow missed your comments about wine which I have had with dinner until recently. I have not seen any change or improvement at all in my senses of taste or smell. I will forego all wine for a while, but also plan to be evaluated for hypothyroidism and perhaps start taking thyroid medication. Though I don’t like the idea of any medication, I do think the thyroid governs a lot of different things in our bodies.
As another said above, it is nice to find someone who understands.
Tina Will
Hi Tina, thanks for your comment. I’m glad you found it interesting. I’m not sure about the thyroid function, it wasn’t something I investigated but may be worth doing so.
The ALA connection was a study I came across from Germany. Link here: https://www.researchgate.net/publication/11029270_Lipoic_Acid_in_the_Treatment_of_Smell_Dysfunction_Following_Viral_Infection_of_the_Upper_Respiratory_Tract
It took about six months I think to notice a slight difference. I still take 250mg most days and my smell is mostly normal now, but can be still killed off for days by overindulgence with wine. (a glass with dinner should be fine though).
It’s greatly underestimated the degree to which no sense of smell can impact your life. I remember it all too well, but also the impact even the first faint inklings of a return had on lifting the spirits.
Best wishes
Michael
Thanks for sharing. I can only smell for a day about once every 3 months. When I can smell I start sneezing and then I lose the ability to smell and taste again. I do find that if I exercise hard where my body is overheating then I can taste and smell until my body cools off. I have this for about 10 years. I have been to 2 nose specialists. They prescribed steroids. One put some solution down my nose to take pictures of my canal. That really messed me up where I lost my sense of smell for about 6 months and I was out $550. It is not fun to not be able to smell and taste. Thanks for this post. I just took my first 200 mg dose of alpha Lipoic acid. I am praying this will work.
Thanks for writing Ben. I hope it works out for you. It took a while for me to notice a difference – about six months properly, but it certainly worked for me. Regards and best wishes, Michael.
hi bencook. I have exact same for the last 6-7 years. No smell or taste at all, only after heavy exercises it comes back for 5-10 minutes and only sometimes. I have started ALA for the last 2 weeks. So far no changes.. but not loosing hope, as I have nothing to loose anyway at this point. Did it get any better for you?
Anddor503,
I have not been taking the ALA very consistent like I should be so I had still been struggling with my taste and smell where I have had nothing until this past December 2021. I went with my wife to visit her sister in Denver, CO. I am from Indiana where the humidity is typically high. In Colorado the humidity was lower. We were in Denver for about a week. Towards the end of the trip I could smell and taste chocolate and coffee about half way. I was super excited. I lost my smell and taste again when we got back until about a month ago I have had episodes where I could smell smoke from a fire a little bit, I smelled a skunk close by. I have been able to smell a little off and on recently. I have taken a little bit of generic Benadryl if I start sneezing to keep my nose dried out. I continue to take ALA but need to more consistently. It has been about 10 to 15 years since I have been able to smell and taste well. The past 4 months have been good. So don’t give up. It is a marathon.
This sounds very promising. After such a long time without scent or taste, even little awakenings bring immense joy.
I am so glad I am not alone! I had a sinus infection 17 years ago and the situs infection was gone and took my sense of smell and taste with it, that lasted 10 years. Every ENT I went to shoved the camera up my nose, told me I had a lot of mucus and sent me home with a steroid – thanks for nothing! So after investigating on my own I Started using the net pot and started getting my senses back little by little. Over the last few years it has come and gone literally sometimes for weeks, sometimes I can smell one hour and not the next. My nutritionist recommended carnosine and that seems to be helping as well.
Hello
Is this still an active chat channel
Hi Wanita, this was one of several pieces I did when I was suffering from no sense of smell. Some got more attention than others, but none really formed a focus for chat or group interest. The blog is still very much alive though.